Nur die allerletzten medizinischen Publikationen bezüglich Zusammenhang zw. HIV und CD4:
1: Parisi SG, Boldrin C, Andreis S, Ferretto R, Fuser R, Malena M, Manfrin V,
Panese S, Scaggiante R, Dori L, Sarmati L, Biasolo MA, Nicastri E, Andreoni M,
Cruciani M, Palù G.
KSHV DNA viremia correlates with low CD4+ cell count in
Italian males at the time of diagnosis of HIV infection. J Med Virol. 2011
Mar;83(3):384-90. doi: 10.1002/jmv.21987. PubMed PMID: 21264857.
2: Phiri R, Feller L, Blignaut E.
The severity, extent and recurrence of
necrotizing periodontal disease in relation to HIV status and CD4+ T cell count.
J Int Acad Periodontol. 2010 Oct;12(4):98-103. PubMed PMID: 21128527.
3: Qaqa AY, Shaaban H, DeBari VA, Phung S, Slim J, Costeas CA, Perez G, Shamoon
FE.
Viral load and CD4+ cell count as risk factors for prolonged QT interval in
HIV-infected subjects: a cohort-nested case-control study in an outpatient
population. Cardiology. 2010;117(2):105-11. Epub 2010 Oct 21. PubMed PMID:
20962525.
4: Lichtenstein KA, Armon C, Buchacz K, Chmiel JS, Buckner K, Tedaldi EM, Wood K,
Holmberg SD, Brooks JT; HIV Outpatient Study (HOPS) Investigators.
Low CD4+ T
cell count is a risk factor for cardiovascular disease events in the HIV
outpatient study. Clin Infect Dis. 2010 Aug 15;51(4):435-47. PubMed PMID:
20597691.
5: Phillips AN, Lampe FC, Smith CJ, Geretti AM, Rodger A, Lodwick RK, Cambiano V,
Tsintas R, Johnson MA.
Ongoing changes in HIV RNA levels during untreated HIV
infection: implications for CD4 cell count depletion. AIDS. 2010 Jun
19;24(10):1561-7. PubMed PMID: 20505495.
6: Prosperi MC, Cozzi-Lepri A, Castagna A, Mussini C, Murri R, Giacometti A,
Torti C, Costantini A, Narciso P, Ghinelli F, Antinori A, d'Arminio Monforte A;
Icona Foundation Study Group.
Incidence of malignancies in HIV-infected patients
and prognostic role of current CD4 cell count: evidence from a large Italian
cohort study. Clin Infect Dis. 2010 May 1;50(9):1316-21. PubMed PMID: 20297953.
Und hier eine Feststellung von der Medizinergruppe unter 5:
CONCLUSION: The often substantial increases in HIV RNA level observed in untreated HIV infection appear fundamentally linked to CD4 cell count depletion. Research into mechanisms by which HIV RNA levels rise over time should yield insights into the causes of CD4 cell count depletion, as the two processes are intimately linked.